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Is there any view of what is best for stress in general? HIT or zone 2 type exercise? Which removes cortisol better or is better for stress overall?

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Great question.

HIIT is certainly more *stressful* in general. More cortisol during and after. But some people report a greater anti-stress effect after. Zone 2 will induce less cortisol overall vs. HIIT. Hard to say which is “better” because it may depend on what you enjoy doing.

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Do you really think that the bodies of the participants cleared out the senescent cells that fast? I honestly highly doubt that. And why would the marker then rise again that steeply in 24 h? Are the cells back to being senescent again after a short period of normal function? Or have the participants "restocked" a fixed pool of senescent cells?

I rather think that this is a typical marker/outcome problem. Further, there are several functions to this protein (see for example here:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501954/

).

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