Archive - Physiologically Speaking

Physiology Friday #313: A “Molecular Brake” on Fitness Explains Why Some People Don’t Respond to Exercise

Have scientists discovered the trainability gene?

8 hrs ago • Brady Holmer

Physiology Friday #312: An Inconsistent Bedtime Doubles Cardiovascular Disease Risk

The stability of when you sleep might be as important as how long you're in bed.

Apr 3 • Brady Holmer

March 2026

Why VO₂ Max Still Matters

Is it still a biomarker of health and longevity?

Mar 30 • Brady Holmer

Physiology Friday #311: Does Being Fitter Protect against Depression and Dementia?

What's good for the heart is good for the brain.

Mar 27 • Brady Holmer

Physiology Friday #310: Should Athletes Supplement with Antioxidants?

As always: it depends.

Mar 20 • Brady Holmer

Physiology Friday #309: Does Exercise “Age You Faster” If You Don’t Sleep Enough?

The viral sleep and exercise claim that took off, and why it’s wrong.

Mar 13 • Brady Holmer

Physiology Friday #308: Post-Exercise Ketones Amplify Endurance Training Benefits

Could a simple supplement help you squeeze more out of your workout?

Mar 6 • Brady Holmer

Live with Brady | 3.2.26

A recording from Brady Holmer's live video

Mar 2 • Brady Holmer

16:30

February 2026

Physiology Friday #307: Should Exercise Guidelines Be Personalized?

Cardiovascular risk should be part of the equation when considering how much activity someone does (and how hard it should be).

Feb 27 • Brady Holmer

Live with Brady | Is VO2 Max Cancelled?

A recording from Brady Holmer's live video

Feb 25 • Brady Holmer

27:54

Live with Brady | 2.23.26

A recording from Brady Holmer's live video

Feb 23 • Brady Holmer

25:58

Physiology Friday #306: How Exercise Hardwires the Brain for Endurance

A special set of neurons directs adaptation and recovery immediately after a workout.

Feb 20 • Brady Holmer

#nojs-banner { position: fixed; bottom: 0; left: 0; padding: 16px 16px 16px 32px; width: 100%; box-sizing: border-box; background: red; color: white; font-family: -apple-system, "Segoe UI", Roboto, Helvetica, Arial, sans-serif, "Apple Color Emoji", "Segoe UI Emoji", "Segoe UI Symbol"; font-size: 13px; line-height: 13px; } #nojs-banner a { color: inherit; text-decoration: underline; } This site requires JavaScript to run correctly. Please turn on JavaScript or unblock scripts